Accession Number : AD0759737

Title :   Ultrastructural Cognates of Mammalian Freeze-Thaw Survival Curves in vitro.

Descriptive Note : Final technical rept. 1 May 69-30 Apr 72,

Corporate Author : OKLAHOMA UNIV FOUNDATION INC OKLAHOMA CITY MEDICAL CENTER RESEARCH AND DEVELOPMENT OFFICE

Personal Author(s) : Miller,Leonard R.

Report Date : 10 APR 1973

Pagination or Media Count : 21

Abstract : The author has defined patterns of cellular injury and repair following exposure of the L5178y Murine Lymphoblasts to 4C. Anatomic studies uncovered severe injury at variance with minimal damage defined by growth and/or survival curves. Additional studies included monolayer cultures of normal and galactosemic human fibroblasts and differentiated gastric mucosal cells. Studies on mitochondrial enzyme localization and damaged mitochondrial functional reconstitution are also reported. (Author)

Descriptors :   (*CELLS(BIOLOGY), FREEZING), WOUNDS AND INJURIES, DAMAGE, ELECTRON MICROSCOPY, MEMBRANES(BIOLOGY), SURVIVAL(PERSONNEL), VIABILITY, MITOCHONDRIA, ENZYMES, IN VITRO ANALYSIS

Subject Categories : Biology

Distribution Statement : APPROVED FOR PUBLIC RELEASE