Accession Number : AD0762101

Title :   Development of an Anticonvulsant Agent Based on its Effect on Gamma-Aminobutyric Acid Metabolism,

Corporate Author : SASKATCHEWAN UNIV SASKATOON DEPT OF BIOCHEMISTRY

Personal Author(s) : Wood,J. D. ; Peesker,S. J. ; Urton,J. I. M.

Report Date : 18 AUG 1972

Pagination or Media Count : 4

Abstract : The administration of isonicotinic acid hydrazid (2.2 mmol/kg) plus pyridoxine (4.4 mmol/kg) to chicks 14-18 h prior to exposure to hyperbaric oxygen provided excellent protection against the onset of oxygen-induced seizures in the birds. (Author)

Descriptors :   (*ANTICONVULSANTS, *HETEROCYCLIC COMPOUNDS), (*AMINO ACIDS, ANTICONVULSANTS), METABOLISM, PHARMACOLOGY, CHICKENS, BIRDS, EXPERIMENTAL DATA

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE