Accession Number : AD0763516

Title :   Chemoreception in the Blood-Feeding Bug Rhodnius Prolixus: A Possible Role of Cyclic AMP,

Corporate Author : TORONTO UNIV (ONTARIO) DEPT OF ZOOLOGY

Personal Author(s) : Smith,J. J. B. ; Friend,W. G.

Report Date : 01 JUN 1972

Pagination or Media Count : 7

Abstract : The gorging response of the blood-feeding bug, Rhodnius prolixus, to the stimulating nucleoside phosphates ATP, ADP, and UTP is significantly enhanced by the presence of the drugs theophylline or caffeine. These drugs may be acting in a manner similar to that in hormonal systems by decreasing the breakdown of the intracellular messenger cAMP. A mechanism is proposed in which extracellular gorging stimulants initiate spike potentials by increasing cAMP production inside the chemoreceptive cells. Such a mechanism would explain how the chemoreceptors can function in 'abnormal' extracellular environments such as a solution of ATP and potassium chloride. (Author)

Descriptors :   (*CHEMORECEPTORS, *INSECTS), BIOCHEMISTRY, ADENOSINE PHOSPHATES, NUCLEOSIDES, STIMULATION(PHYSIOLOGY), DRUGS, PHYSIOLOGY, CANADA

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE