Accession Number : AD0763922

Title :   Investigations of Attenuated Strains of Group a Arboviruses.

Descriptive Note : Annual summary rept. no. 1, 1 Jul 72-30 Jun 73,

Corporate Author : VIRGINIA COMMONWEALTH UNIV RICHMOND

Personal Author(s) : Coleman,Philip H. ; Formica,Joseph V.

Report Date : 30 MAR 1973

Pagination or Media Count : 15

Abstract : The purpose of the study is two-fold: First, to isolate a strain of eastern equine encephalitis (EEE) virus which has lost its virulent characteristics for animals and man but retains its immunogenic properties; and second, to characterize the clone 15 strain of attenuated western equine encephalitis (WEE) virus to determine its suitability as a vaccine for man and animals. EEE and WEE vaccines are necessary in order to immunize researcher and diagnosticians working with these viruses, veterinarians and others working with infected animals and special groups such as military personnel who might be exposed to natural infections because of their assignments in endemic or epidemic areas of viral activity.

Descriptors :   (*GROUP A ARBOVIRUSES, ATTENUATION), (*EASTERN EQUINE ENCEPHALOMYELITIS VIRUS, VACCINES), (*WESTERN EQUINE ENCEPHALOMYELITIS VIRUS, VACCINES), ARBOVIRUSES, MUTATIONS, VIRUS DISEASES, IMMUNITY

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE