Accession Number : AD0764220

Title :   Primary Irritation Evaluation Program Study.

Descriptive Note : Final rept.,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Briel,Jonathan ; Stine,Rudy

Report Date : MAY 1973

Pagination or Media Count : 7

Abstract : ENT-35523-Ga, ENT-35662-Ga, and ENT-70515-Ga which are candidate repellents, were evaluated on New Zealand White rabbits for their potential to cause skin irritation. The data obtained serve as a basis for making a recommendation concerning their potential use on humans. This recommendation is intended only for guidance in further entomological testing of these compounds. It does not constitute approval for testing on human volunteers. The interpretation of the three compounds is that they should be used only on human skin found by examination to have no abrasions or may be used as a clothing impregnant. However, if the compounds might come in contact with abraded skin, a prophetic patch test should be conducted on human skin to determine primary irritation potential. (Author)

Descriptors :   (*INSECT REPELLENTS, *TOXICITY), SKIN(ANATOMY), EYE, HUMANS, BIOASSAY, RABBITS, PIPERIDINES, KETONES, ORGANIC SULFUR COMPOUNDS

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE