Accession Number : AD0765465

Title :   Clotting Factors of Supernatant Plasma Following Cryoprecipitation.

Descriptive Note : Final rept.,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Roth,Gerald J. ; Tobias,Kenneth I. ; Eaton,James A. , Jr. ; Kline,William E. ; Rudai,Thomas A.

Report Date : 28 FEB 1973

Pagination or Media Count : 11

Abstract : The supernatant plasma which remains after cryoprecipitation is a useful component for transfusion therapy. However, from prior studies it was unclear how well plasma clotting factors were preserved following cryoprecipitation. Coagulation factor assays were performed on fresh plasma, supernatant plasma after removal of cryoprecipitate and the same supernatant plasma following refreezing and thawing. Factor VIII and fibrinogen levels fall considerably after removal of cryoprecipitate, but there were also significant declines in factors V and VII. Refreezing and thawing the supernatant plasma had little effect on most clotting factors. (Author)

Descriptors :   (*BLOOD PLASMA, FREEZING), (*BLOOD COAGULATION, BLOOD PLASMA), BLOOD TRANSFUSION, FIBRINOGEN, CHEMICAL PRECIPITATION

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE