Accession Number : AD0767342

Title :   Prostaglandins and the Lung

Descriptive Note : Technical rept.

Corporate Author : OKLAHOMA UNIV FOUNDATION INC OKLAHOMA CITY MEDICAL CENTER RESEARCH AND DEVELOPMENT OFFICE

Personal Author(s) : Nakano,Jiro ; McCloy,Robert B. , Jr.

Report Date : 18 JUN 1973

Pagination or Media Count : 57

Abstract : The prostaglandins exert multiple potent pharmacological actions on different organs and tissues including the respiratory system. Although it is rather premature to conclude the precise physiological and pathophysiological roles of prostaglandins at the present time, a large number of recent observations implicate a close relationship between prostaglandins and pathogenesis and clinical manifestations of pulmonary disease. With reasonable certainty, the pathophysiological roles of the prostaglandins in respiratory disease will be clarified, along with a better understanding of pulmonary disease mechanisms. Furthermore, one can anticipate the synthesis of more potent and specific prostaglandin antagonists which may prove valuable in the treatment of respiratory disease. (Author)

Descriptors :   (*Carboxylic acids, Pharmacology), (*Lung, Carboxylic acids), Respiratory system, Respiratory diseases, Physiology, Pathology, Chemotherapeutic agents, Biosynthesis

Subject Categories : Biochemistry
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE