Accession Number : AD0767385

Title :   Prostaglandin Release and Metabolism during Different Physiological States.

Descriptive Note : Final rept. 1 Jul 70-28 Feb 73,

Corporate Author : STANFORD UNIV CALIF DEPT OF PHYSIOLOGY

Personal Author(s) : Ramwell,Peter W.

Report Date : 28 FEB 1973

Pagination or Media Count : 12

Abstract : The work performed resulted in the development of an improved method for the separation and storage of platelets for transfusion purposes. Basic studies have explored potential side effects, prostaglandin metabolism, prostaglandin binding to plasma constituents, prostaglandin enzyme sites of action and finally the stereochemical requirements of prostaglandins for biological activity.

Descriptors :   (*CARBOXYLIC ACIDS, *BLOOD PLATELETS), (*BLOOD TRANSFUSION, CARBOXYLIC ACIDS), (*BLOOD PLATELETS, STORAGE), METABOLISM, ENZYMES, SALICYLIC ACIDS, MOLECULAR STRUCTURE, STORAGE, PRESERVATION, FEVERS, HEMATOLOGY

Subject Categories : Anatomy and Physiology
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE