Accession Number : AD0767748

Title :   Korean Hemorrhagic Fever.

Descriptive Note : Annual rept. no. 4, 10 Dec 71-8 Dec 72,

Corporate Author : SEOUL NATIONAL UNIV (REPUBLIC OF KOREA) COLL OF MEDICINE

Personal Author(s) : Lee,Ho Wang

Report Date : 23 APR 1973

Pagination or Media Count : 46

Abstract : Korean hemorrhagic fever (KHF) occurred for the first time in Korea, 1951, although it had previously been known to both the Japanese and Russians. After Korean war, the disease has been fixed in the areas of DMZ as an endemic one, and from 100 to 300 cases have been reported every year. The aims of this project are epidemiologic investigation of the disease in the civilian endemic areas, to isolation of the causative agent of KHF, and demonstration of specific antibodies of KHF by fluorescent antibody technic. The outbreak of patients had been localized in the vicinity of DMZ until 1970 but in 1971 affected the middle districts and in 1972 invaded the southern parts of South Korea. The number of patients and the areas of KHF in 1972 were investigated extensively and found there were 389 hospitalized cases with 7.7% fatality. Field rodents were collected and their ecto-parasites were classified. The populations of field rodents and their ecto-parasites were greatest when the incidence of KHF reached its peak. The attempts to isolate the etiologic agent from patients resulted in failure but 10 strains of unknown agents were isolated from rodents collected in the endemic foci of KHF in 1972. Incidence of Au-antigen in the KHF patients were 7% among 170 tested sera. (Modified author abstract)

Descriptors :   (*VIRUS DISEASES, *SOUTHEAST ASIA), (*ARBOVIRUSES, VIRUS DISEASES), EPIDEMIOLOGY, ETIOLOGY, IMMUNOLOGY, FLUORESCENT ANTIBODY TECHNIQUES, DISEASE VECTORS, RODENTS, SERODIAGNOSIS

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE