Accession Number : AD0767762

Title :   Primary Irritation Evaluation Program Study.

Descriptive Note : Final rept.,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Briel,Jonathan ; Malloy,John

Report Date : 09 JUL 1973

Pagination or Media Count : 7

Abstract : 1-(Butylsulfonyl)-1,2,3,6-tetrahydropyridine (ENT 35898-Ga), 1,2,3,6-tetrahydro-1-(propylsulfonyl) pyridine (ENT 35899-Ga) and 1-(ethylsulfonyl)-1,2,3,6-tetrahydropyridine (ENT 35900-Ga) which are candidate repellents, were evaluated on New Zealand White rabbits for their potential to cause skin irritation. The data obtained serve as a basis for making a recommendation concerning their potential use on humans. This recommendation is intended only for guidance in further entomological testing of these compounds and does not constitute approval for testing on volunteers. (Author)

Descriptors :   (*INSECT REPELLENTS, *TOXICITY), (*PYRIDINES, INSECT REPELLENTS), SKIN(ANATOMY), IRRITATING AGENTS, BIOASSAY, HUMANS, RABBITS, ORGANIC SULFUR COMPOUNDS

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE