Accession Number : AD0768866

Title :   Development of Analytical Methods for the Determination of Experimental Antimalarials in Biological Fluids.

Descriptive Note : Annual rept. Jul 72-Jun 73,

Corporate Author : LITTLE (ARTHUR D) INC CAMBRIDGE MASS

Personal Author(s) : Burg,Alan W.

Report Date : 31 AUG 1973

Pagination or Media Count : 60

Abstract : Experimental work has been conducted to allow the development of analytical methods for the determination of antimalarial drugs in biological fluids. Both spectrofluorometric and gas chromatographic techniques have been applied to the analysis of WR 33063, WR 122455 and WR 171669 in human plasma. All developmental work has been based upon the potential utility of such methods to the clinical trial of new drugs. (Modified author abstract)

Descriptors :   (*ANTIMALARIALS, BLOOD PLASMA), (*BLOOD PLASMA, CHEMICAL ANALYSIS), FLUORESCENCE, EXPERIMENTAL DATA, CHEMOTHERAPEUTIC AGENTS, GAS CHROMATOGRAPHY, DRUGS, SPECTROSCOPY, DRUGS

Subject Categories : Biochemistry
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE