Accession Number : AD0768867

Title :   World Reference Center for Arboviruses.

Descriptive Note : Annual progress rept. 1 Jul 72-30 Jun 73,

Corporate Author : YALE UNIV NEW HAVEN CONN SCHOOL OF MEDICINE

Personal Author(s) : Shope,Robert E.

Report Date : 01 JUL 1973

Pagination or Media Count : 77

Abstract : The Yale Arbovirus Research Unit serves the military and other agencies as an arbovirus reference center to identify viruses, serologically diagnose disease, prepare and distribute reference reagents and virus stocks, conduct serological surveys, and develop new techniques in arbovirology. Viruses and/or antisera to 197 strains were received from 20 foreign countries and the USA for identification. Those identified included 2 new Kemerovo group viruses, a new rabies-related agent, and 11 known viruses from new geographical areas. Serological classifications in the DGK, Changuinola, and arbo-A groups were made or revised. A presumed insect-pathogenic virus was characterized in mosquito cell culture. The reference center distributed 1385 ampoules of reagents to laboratories in the USA and 19 other countries. Mosquito and mammalian cell cultures were supplied to laboratories in the USA and six other nations. Sero survey in British Honduras showed that the HI test was useful to evaluate VEE vaccine. Another survey in Iran demonstrated Crimean hemorrhagic fever virus antibody in a wide variety of animals and man. (Modified author abstract) Portions of this document are not fully legible.

Descriptors :   (*ARBOVIRUSES, STANDARDS), IMMUNE SERUMS, IDENTIFICATION, CLASSIFICATION, SERODIAGNOSIS, TISSUE CULTURE, CULICIDAE, MAMMALS, VIRUS DISEASES, VIRUSES

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE