Accession Number : AD0768935

Title :   Experimente ueber den Einflusse von Metaboliten und Antimetaboliten am Modell von Trichomonas Vaginalis. VIII. Mitteilung: Experiments mit Hormonen (Experiments on the Influence of Metabolites and Antimetabolites on the Model of Trichomonas Vaginalis. VIII. Communication: Experiments with Hormones),

Corporate Author : ROBERT KOCH-INSTITUT BERLIN (WEST GERMANY)

Personal Author(s) : Christow,Chr. Petrow

Report Date : 30 SEP 1970

Pagination or Media Count : 12

Abstract : The present study has been concerned with the influence of some hormones upon trichomonas growth. The following substances were used for our experiments: serotonin, oestron, progesteron, hydroxyprogesteron, adrenalin, testosteron, methyltestosteron, and the antihoromone 3.5-dijodtyrosine. The experiments were performed on 7 trichomonas vaginalis strains. The test cultures with serotonin, oestron, testosteron and methyltestosteron grew at concentrations from 0.20 to 6.0 mg/ml as well as the control cultures. Inhibiting action, especially at a concentration of 0.80 mg/ml could be demonstrated in the experiments with progesteron. Slightly inhibiting action was noted in the experiments with hydroxyprogesteron from concentrations of 3.0 mg/ml onward. Adrenalin and noradrenalin have generally inhibiting action (from 0.80 mg/ml onward) upon trichomonas growth. The antihormone 3.5-dijodtyrosin does rarely influence the growth of trichomonas. (Author)

Descriptors :   (*PROTOZOA, REPRODUCTIVE SYSTEM), (*HORMONES, PROTOZOA), METABOLISM, GROWTH(PHYSIOLOGY), PARASITES, SEX HORMONES, TESTOSTERONE, WEST GERMANY

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE