Accession Number : AD0769487

Title :   Effects of Neutron Irradiations on Nerve Tissue Cultures. Part II. Instrumentation for Remote Electrical Recording from Neurons in Culture.

Descriptive Note : Final rept. Dec 71-Dec 72,

Corporate Author : CALIFORNIA UNIV BERKELEY LAWRENCE LIVERMORE LAB

Personal Author(s) : Gahwiler,B. ; Mamoon,A. ; Schimmerling,W. ; Tobias,C. A.

Report Date : SEP 1973

Pagination or Media Count : 11

Abstract : In preparing to investigate the effects of 14-Mev neutron irradiation of neural cell cultures, a compact device was built to expose and simultaneously record electrical activity of the neural explants. Unique features include a vibration-free table mounting, a homeostatic nutrition flow and temperature control during electrical recording from microelectrodes, remote scanning, with movement in increments of less than one micron, with closed-circuit television monitoring, and a laser beam optical system which allows for stimulation of the neurons in response to preselected firing patterns. (Author)

Descriptors :   (*Nervous system, Tissue culture), (*Neutrons, Irradiation), (*Irradiation, Nervous system), (*Recording systems, Instrumentation), Bioelectricity, Remote systems, Cultures(Biology), Electrophysiology, Lasers, Temperature control

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE