Accession Number : AD0769487
Title : Effects of Neutron Irradiations on Nerve Tissue Cultures. Part II. Instrumentation for Remote Electrical Recording from Neurons in Culture.
Descriptive Note : Final rept. Dec 71-Dec 72,
Corporate Author : CALIFORNIA UNIV BERKELEY LAWRENCE LIVERMORE LAB
Personal Author(s) : Gahwiler,B. ; Mamoon,A. ; Schimmerling,W. ; Tobias,C. A.
Report Date : SEP 1973
Pagination or Media Count : 11
Abstract : In preparing to investigate the effects of 14-Mev neutron irradiation of neural cell cultures, a compact device was built to expose and simultaneously record electrical activity of the neural explants. Unique features include a vibration-free table mounting, a homeostatic nutrition flow and temperature control during electrical recording from microelectrodes, remote scanning, with movement in increments of less than one micron, with closed-circuit television monitoring, and a laser beam optical system which allows for stimulation of the neurons in response to preselected firing patterns. (Author)
Descriptors : (*Nervous system, Tissue culture), (*Neutrons, Irradiation), (*Irradiation, Nervous system), (*Recording systems, Instrumentation), Bioelectricity, Remote systems, Cultures(Biology), Electrophysiology, Lasers, Temperature control
Subject Categories : Radiobiology
Distribution Statement : APPROVED FOR PUBLIC RELEASE