Accession Number : AD0771121
Title : Synthesis of New Antimalarial Drugs (1- and 9-Anthraceneaminoalcohols).
Descriptive Note : Rept. no. 4 (Final) 1 Jun 72-31 May 73,
Corporate Author : INTERNATIONAL MINERALS AND CHEMICAL CORP LIBERTYVILLE ILL
Personal Author(s) : Traxler,James T. ; Moats,Mary J. ; Lira,E. Patrick ; Huffman,Clarence W.
Report Date : JUL 1973
Pagination or Media Count : 52
Abstract : The synthesis of seven anthracene aminoalcohols with one or two additional substituents is described. These compounds include three 1-aminoethanols, two 9-aminoethanols and two 9-aminopropanols, prepared from commercially-available substituted anthraquinones or from 10-chloroanthraldehydes. The synthesis of 1-aminoethanols from substituted benzanthrones was shown capable of producing compounds already available by means of less complex schemes. (Modified author abstract)
Descriptors : *Antimalarials, *Anthracenes, *Ethanols, *Propanols, *Synthesis(Chemistry), Aldehydes, Chlorine compounds, Amines, Chemical reactions, Halogenated hydrocarbons, Bromine compounds, Iodine compounds
Subject Categories : Pharmacology
Distribution Statement : APPROVED FOR PUBLIC RELEASE