Accession Number : AD0773903

Title :   Experimental Study of the Allergenic Action of Ortho- and Para-Nitrochlorobenzene,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Rusakov,N. V. ; Korotkova,G. I. ; Bikbulatov,V. Sh.

Report Date : 17 JAN 1974

Pagination or Media Count : 13

Abstract : Various compounds of benzene are included among wide-spread atmospheric contaminants. The compounds ortho-nitrochlorobenzene (ONCB) and para-nitrochlorobenzene (PNCB) can be found in the air over populated places in contents which exceed the permissible standard. It should be noted that the discharges from production of nitrochlorobenzene usually contain a complex of its isomers. During industrial preparation of ONCB and PNCB the compound 2,4-dinitrochlorobenzene (2, 4-DNCB) is formed as a by-product. It is known that 2,4-DNCB possesses sharply expressed allergenic properties. Results of tests on the sensitization of animals to this compound are reported.

Descriptors :   *Nitrobenzenes, *Allergic diseases, *Industrial medicine, Toxicology, Immunology, USSR, Translations, Laboratory animals, Experimental data

Subject Categories : Toxicology
      Environmental Health and Safety

Distribution Statement : APPROVED FOR PUBLIC RELEASE