Accession Number : AD0775891

Title :   Acute Changes in Oxyhemoglobin Affinity Effects on Oxygen Transport and Utilization.

Descriptive Note : Technical rept.,

Corporate Author : OKLAHOMA UNIV HEALTH SCIENCES CENTER OKLAHOMA CITY

Personal Author(s) : Riggs,Thomas E. ; Shafer,A. William ; Guenter,Clarence A.

Report Date : 04 JAN 1974

Pagination or Media Count : 13

Abstract : It has been postulated that 2,3-diphosphoglycerate (DPG)-mediated changes in oxyhemoglobin affinity play an important role in oxygen delivery; however, the effect of an acute increase in affinity without changing red cell mass has not been systematically evaluated. This study was designed to measure changes in oxygen transport and oxygen consumption produced by an acute increase in oxyhemoglobin affinity caused by an autologous exchange transfusion using DPG-depleted stored blood. (Modified author abstract)

Descriptors :   *Oxygen consumption, *Blood transfusion, Oxygen, Hemoglobin, Blood, Storage, Blood circulation, Physiology

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE