Accession Number : AD0776744

Title :   Effect of Certain Antimetabolites and of Chloramphenicol on Conjugation of E. coli K-12,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Belousova,I. I. ; Tereshin,I. M.

Report Date : 11 MAR 1974

Pagination or Media Count : 6

Abstract : There is major interest in studying the role of processes of transfer of genetic information in bacteria -- conjugation, transformation, and transduction -- in the appearance and propagation of antibiotic-resistant forms of microorganisms. Many researchers have established that by means of the above genetic processes it is possible to transform strains of certain types of bacteria which are sensitive to antibiotics into antibiotic-resistant organisms. The authors studied the effect of chloramphenicol, 5-bromouracil (5-BU), and 8-azaguanine (8-AG) on the conjugation of E. coli K-12 on the transfer of genetic markers from the donor to the recipient.

Descriptors :   *Escherichia coli, *Genetics, *Antibiotics, *Antimetabolites, Resistance(Biology), Bacteria, Reproduction(Physiology), Drugs, Translations, USSR

Subject Categories : Microbiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE