Accession Number : AD0776927

Title :   Correlation of Plasma Volume and Body Weight in Dogs,


Personal Author(s) : Nims,Robert M. ; Vacca,Joseph B. ; Blair,Doyce T. ; Waring,Paul P.

Report Date : SEP 1973

Pagination or Media Count : 22

Abstract : Plasma volumes were determined in 74 experiments on 35 dogs using a T-1824 dye procedure. These values were correlated with body weights in order to examine the relationship and ascertain the reliability of estimating plasma volume from body weight. Further clarification of the relationship was achieved by a comparison with 290 additional plasma volume measurements obtained from the literature. Statistical analyses indicated that the overall data provided the most reliable formula for predicting plasma volume from body weight, but the estimated value contained a potential deviation of plus or minus 244 ml. from the actual value. This variability was not explained by differences in experimental techniques nor measurement error but appeared to be characteristic of the plasma volume/body weight relationship. The total data expressed as plasma volume/kg. body weight approached a normal distribution and indicated that the 'normal range' for plasma volumes in dogs was 34.3 ml./kg. to 69.4 ml./kg. with a mean of 51.8 ml./kg. (Author)

Descriptors :   *Blood plasma, *Body weight, *Blood volume, Correlation techniques, Dogs, Laboratory animals, Statistical analysis, Experimental data, Physiology, Veterinary medicine, Nutrition

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE