Accession Number : AD0778530

Title :   Effect of Polyene Antifungal Antibiotics on Glycolysis in Animal Tissues,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Lutvinova,V. N.

Report Date : 18 APR 1974

Pagination or Media Count : 7

Abstract : According to literature data certain polyene antibiotics inhibit glycolysis in the bacterial and yeast cell. Polyene antibiotics also have a strong toxic effect on the animal organism. In connection with this the question arises of clarifying the effect of antibiotics on metabolism in the living organism. For this purpose a study was made of the effect of polyene antifungal antibiotics - the sodium salt of nystatin, pentaene 1454/69, and hexaene 868/9 - on glycolysis in brain tissue and erythrocytes.

Descriptors :   *Antibiotics, *Glycolysis, *Fungi, Experimental data, Mice, Metabolism, Alkenes, Tissues(Biology), USSR, Translations

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE