Accession Number : AD0778587

Title :   On Amino Acid Metabolism in the Griseofulvin Producer 'Pen. nigricans Thom',

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Efimova,T. P.

Report Date : 15 APR 1974

Pagination or Media Count : 7

Abstract : A total of 18 amino acids were detected in the mycelium of P. nigricans. Predominant among these were glutamic acid (38.9 mg per gram of dry mycelium), proline (30.15 mg), and histidine (28.42 mg). In addition a high content of the amino sugar glucosamine was detected. A reduction in the content of individual amino acids in the mycelium was noted on the 9th day of growth; this was more strongly expressed in 12-day mycelium. The content of amino acids in the liquid culture medium was simultaneously increased, which indicated the onset of autolysis.

Descriptors :   *Amino acids, Proteins, Metabolism, Fungi, Cultures(Biology), Culture media, Griseofulvin, Antibiotics, Fungicides, Translations, USSR

Subject Categories : Biochemistry
      Microbiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE