Accession Number : AD0779048

Title :   Influence of Altered Gaseous Environments on Lung Metabolism.

Descriptive Note : Interim progress rept. no. 1, 1 Jun 73-31 May 74,

Corporate Author : PENNSYLVANIA STATE UNIV UNIVERSITY PARK CENTER FOR AIR ENVIRONMENT STUDIES

Personal Author(s) : Rhoades,Rodney A.

Report Date : MAR 1974

Pagination or Media Count : 25

Abstract : To date, the main findings of this investigation indicate the acute hypoxic stress (1.5 hr. to PO2 34mmHg) does not markedly accelerate glucose uptake, decrease lipid synthesis, deplete tissue glycogen, or shut down citric acid cycle activity with a concomitant decrease in glucose and fatty acid oxidation; effects commonly seen in other organs. Thus, the lung appears to be more resistant to hypoxic stress. Finally, exposure to hyperoxia for 1.5 hr. has little detrimental effect on the metabolic process of the lung. (Author)

Descriptors :   *Lung, *Hypoxia, *Metabolism, Glucose, Fatty acids, Stress(Physiology), Oxygen

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE