Accession Number : AD0779650

Title :   Searches for Psychotropic Substances among Derivatives of Pyrazino (1,2-a) Indole,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Andreev,N. I.

Report Date : 18 APR 1974

Pagination or Media Count : 5

Abstract : The pharmacological study of a number of derivatives of pyrazino (1,2-a) indole was conducted with the following indicators: the effect of the compounds on spontaneous and caused reactions in mice and rats; the influence on the central effects of phenamine, and the peripheral effects on adrenalin, noradrenaline, serotonin, reserpine, and analgesics, and locally anesthetizing substances; and on the convulsive activity of nicotine, arecoline, and corazole.

Descriptors :   *Indoles, *Psychotropic agents, Nitrogen heterocyclic compounds, Drugs, Pharmacology, Mice, Rats, Bioassay, Toxicity, USSR, Translations

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE