Accession Number : AD0780117

Title :   Development of Mosquito Repellents Having Increased Protection Time in Man.

Descriptive Note : Annual rept. 1 Jul 73-15 Mar 74,

Corporate Author : STANFORD RESEARCH INST MENLO PARK CA

Personal Author(s) : Skinner, W. A. ; Johnson, Howard L. ; Tong, H. C.

Report Date : 15 MAR 1974

Pagination or Media Count : 66

Abstract : Synthetic topical repellents were prepared, following previously reported leads that resulted from intrinsic repellency studies and from Stanford Research Institute (SRI) computed-coded USDA compounds. The most promising structural area for topical repellency continues to be glycol ether derivatives, although the carbamide, 2,4-thiazolidinedione, and quinoxaline areas are also of interest. Efforts were directed toward polymer formulations of SRI glycol ethers to improve their wash-off characteristics and cosmetic acceptability. These studies range from the typical film-formers to carbowax stick-type formulations. Large samples of two 2,4-thiazolidinediones were synthesized for toxicologic evaluation. (Modified author abstract)

Descriptors :   *CULICIDAE, *INSECT REPELLENTS, ETHERS, BEHAVIOR, HUMANS, PROTECTION, GLYCOLS, THIAZOLES, QUINOLINES, SULFONAMIDES, TOXICOLOGY, HUMANS.

Subject Categories : Hygiene and Sanitation
      Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE