Accession Number : AD0780394

Title :   Immunologic Indices during Sensitization of Animals with Antigen from Cultures of 'Trichophyton rubrum',

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Tseitlina,B. B.

Report Date : 24 MAY 1974

Pagination or Media Count : 11

Abstract : A specific allergic state develops after sensitization of guinea pigs by intracutaneous inoculation of T. rubrum vaccine. Allergic tests were used for detection of sensitization: skin tests, Prausnitz-Kustner test, CFT in the cold and anaphylaxy test with desensitization. The skin reaction of the immediate type was observed in 58.3%, of the delayed type--in 97.9% of the animals. Prausnitz-Kustner test was found to be positive in 44.1% of guinea pigs, positive CFT--in 77.5%. All guinea pigs showed a positive anaphylaxy test with desensitization. (Modified author abstract)

Descriptors :   *Fungus diseases, *Diagnostic agents, *Allergic diseases, Sensitivity, Skin(Anatomy), Antigen antibody reactions, Immunology, Guinea pigs, Experimental data, USSR, Translations

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE