Accession Number : AD0781413

Title :   Homologies in Procaryotic Ribosomal Proteins: Alanine Rich Acidic Proteins Associated with Polypeptide Translocation,

Corporate Author : NATIONAL RESEARCH COUNCIL OF CANADA OTTAWA (ONTARIO) DIV OF BIOLOGICAL SCIENCES

Personal Author(s) : Visentin,Louis P. ; Matheson,Alastair T. ; Yaguchi,Makoto

Report Date : 28 JAN 1974

Pagination or Media Count : 5

Abstract : Translocation of the growing peptide chain in the synthesis of proteins is mediated to some extent by certain novel acidic ribosomal proteins. These proteins, designated L7 and L12 in Escherichia coli, are localized on the 50 S ribosomal subunit and differ only in the acetylation state of the N-terminal serine. The isolation, chemical characterization and N-terminal sequence analysis of an L7-L12 equivalent from B. stearothermophilus is reported, and the structural features are compared with the E. coli polypeptides, a comparison that is of particular note in view of the considerable interest in the structure, function and evolution of the genetic translation apparatus.

Descriptors :   *Proteins, *Ribosomes, *Peptides, Escherichia coli, Chemical composition, Amino acids, Molecular structure, Canada

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE