Accession Number : AD0781514

Title :   Possible Role of Nucleotidases in Subcutaneous Calcification.

Descriptive Note : Technical rept.,

Corporate Author : ARMY MEDICAL BIOENGINEERING RESEARCH AND DEVELOPMENT LAB ABERDEEN PROVING GROUND MD

Personal Author(s) : Boke,James W. ; Hegyeli,Andrew F. ; Lambert,Donald H.

Report Date : JUN 1974

Pagination or Media Count : 8

Abstract : The calcium complexes of purine and pyrimidine nucleotides were evaluated in terms of their ability to initiate subcutaneous calcification in vivo. Of the calcium-nucleotide complexes tested, CaATP was most potent. CaTTP and CaGTP were considerably less effective than CaATP, and CaCTP, CaUTP and CaITP were ineffective. These data imply a specificity for CaATP in this phenomenon. (Author)

Descriptors :   *Calcification, *Skin(Anatomy), Enzymes, Nucleotides, Tissues(Biology), In vivo analysis

Subject Categories : Biochemistry

Distribution Statement : APPROVED FOR PUBLIC RELEASE