Accession Number : AD0782595

Title :   Protective Effect of an Elemental Diet on Radiation Enteropathy in the Mouse,

Corporate Author : SHERBROOKE UNIV (QUEBEC) DEPT OF PATHOLOGY

Personal Author(s) : Hugon,J. S. ; Bounous,G.

Report Date : 1973

Pagination or Media Count : 14

Abstract : An elemental diet containing 9.5% protein hydrolysate instead of whole proteins has been shown to improve the 30 days survival in mice following 900 rd of gamma rays. Survival rate and body-weight of different groups of animals receiving diets with 9.5% or 15% protein hydrolsate or whole proteins, given before and after irradiation only after irradiation, have been compared. Intestinal mitotic indices in mice eating the same diets have also been measured following 1000 R of gamma rays. The results show that an elemental diet containing 9.5% protein hydrolysate appears to provide the best survival rate, weight recovery and intestinal mitotic index on condition that the diet is given before irradiation. Some of the reasons explaining this positive effect of the elemental diet are discussed. (Author)

Descriptors :   *Diet, *Radiation effects, *Radiobiology, Gamma rays, Mice, Canada, Intestines, Weight, Survival(General), Proteins, Protection, Irradiation, Canada

Subject Categories : Radiobiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE