Accession Number : AD0782852

Title :   The Effect of Gamma-Globulin on the Reactivity of an Organism,

Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO

Personal Author(s) : Khrometskaya,T. M. ; Tikhonova,N. T. ; Krutkova,A. S. ; Gryaznova,Z. N. ; Kudashov,N. I.

Report Date : 25 JUN 1974

Pagination or Media Count : 13

Abstract : Intramuscular administration of preparations of homologous and heterogeneous gamma-globulin to rabbits was accompanied by the production of antibodies - anti-gammaglobulins whose quantitative amount depends on particular specificity of the preparation and its dose. During the immunization of rabbits with the gamma-globulin the authors observed the usual order of antibody synthesis: the antibodies of the IgM type are formed first and then the IgG type. The administration of gamma-globulin to rabbits was accompanied by the formation of cellular reactions in the lymphoid tissue: activation of reticular cells, an increase in young cellular forms, and a development of the plasmocytic reaction.

Descriptors :   *Gamma globulin, *Immunization, Experimental data, Immunology, Rabbits, Blood proteins, USSR, Translations, Laboratory animals, Children, Antibodies, Lymphatic system

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE