Accession Number : AD0784139

Title :   Experimental Respiratory Infection with 'Pasteurella multocida' and 'Bordetella bronchiseptica' in Rabbits.

Descriptive Note : Technical rept. Feb-Mar 74,

Corporate Author : EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Personal Author(s) : Watson,William T. ; Goldsboro,Jerome A. ; Williams,Fletcher P. ; Sueur,Rebekah

Report Date : JUL 1974

Pagination or Media Count : 13

Abstract : Eight- to ten-weekold offspring of a colony of specific pathogen-free rabbits were exposed to cultures of Pasteurella multocida and Bordetella bronchiseptica. Two groups of nine animals were exposed to either bacterium intranasally and sacrificed 2, 7, 14, and 21 days postinoculation. Five of nine rabbits in each group developed a mucopurulent nasal discharge 4 to 7 days postinoculation. The remaining four rabbits in each group failed to develop clinical signs. The gross and microscopic lesions did not differ significantly in character or distribution among the inoculated rabbits. The infection was characterized by an acute upper respiratory syndrome accompanied by a mild bronchopneumonia. (Author)

Descriptors :   *Respiratory diseases, Pasteurella, Bordetella, Rabbits, Laboratory animals, Experimental data, Infectious diseases, Bacteria, Cultures(Biology), Etiology, Pneumonia

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE