Accession Number : AD0784431

Title :   Possible Role of Interferon in Control of Respiratory Infections in Recruits.

Descriptive Note : Final rept.,

Corporate Author : MEDICAL COLL OF WISCONSIN MILWAUKEE DEPT OF MEDICINE

Personal Author(s) : Rytel,Michael W.

Report Date : 31 AUG 1974

Pagination or Media Count : 15

Abstract : Several vaccines have been reported in the literature as having the potential of interferon induction (1-4). In view of the fact that no other safe and effective interferon inducers are currently available, these vaccines remain the only readily available agents which could be employed for possible prophylactic or therapeutic interferon induction in man. The purpose of this study was to attempt to extend the spectrum of vaccines with known interferon inducing material. Two vaccines were evaluated. One was a commercially available live, oral poliomyelitis vaccine, type 2, and the other a new live, attenuated influenza A/England/42/72 (H3N2) vaccine which is currently undergoing field trials.

Descriptors :   *Respiratory diseases, *Antiviral agents, *Interferon, *Vaccines, Proteins, Infectious diseases, Virus diseases, Poliomyelitis virus, Influenza virus

Subject Categories : Medicine and Medical Research
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE