Accession Number : AD0785210
Title : Experimental Study of the Effect of the Dose of a Chemical Substance on the Incidence and Intensity of Contact Allergy,
Corporate Author : FOREIGN TECHNOLOGY DIV WRIGHT-PATTERSON AFB OHIO
Personal Author(s) : Alekseeva,O. G. ; Barlogova,S. G. ; Dueva,L. A. ; Zagidullin,Sh. Z. ; Raben,A. S.
Report Date : 21 AUG 1974
Pagination or Media Count : 11
Abstract : A direct relationship exists between the dose of a chemical allergen and the intensity of contact allergy. In a large number of chemical allergens, the threshold of allergizing action is below the threshold of toxic action during absorption through the skin. On this basis when setting permissible standards it is not necessary to consider the specific effect. Certain weak allergens can be active sensitizers even in toxic doses.
Descriptors : *Allergic diseases, *Dermatitis, Antigens, Chemical agents, Dosage, Skin(Anatomy), Toxicity, Thresholds(Physiology), Industrial medicine, Immunology, USSR, Translations
Subject Categories : Medicine and Medical Research
Environmental Health and Safety
Distribution Statement : APPROVED FOR PUBLIC RELEASE