Accession Number : AD0800590

Title :   EFFECT OF SUB-ZERO USE OF SPORICIDES PERACETIC ACID AND BETA-PROPIOLACTONE,

Corporate Author : FORT DETRICK FREDERICK MD

Personal Author(s) : Jones, Lynwood A., Jr. ; Hoffman, Robert K. ; Phillips, Charles R.

Report Date : SEP 1966

Pagination or Media Count : 22

Abstract : A method was developed to evaluate and measure the sporicidal activity of peracetic acid (PAA) and beta-propiolactone (BPL) at temperatures as low as -40 C. Bacillus subtilis var. niger spores were used as the test organism. Both PAA and BPL were sporicidal at low temperatures, with PAA the more active. The temperature coefficients of the two chemicals are generally low over a range of +20 to -20 C, but increase significantly at temperatures below this. Results showed an initial lag in the PAA death rates that was directly dependent on the temperature. BPL did not show this lag time. (Author)

Descriptors :   (*GERMICIDES, EFFECTIVENESS), SPORES, LOW TEMPERATURE, BACILLUS SUBTILIS, ACETIC ACID, LACTONES.

Subject Categories : Medical Facilities, Equipment and Supplies

Distribution Statement : APPROVED FOR PUBLIC RELEASE