Accession Number : AD0806400

Title :   EFFECTS OF THE COLD PRESSOR TEST ON GLOMERULAR FILTRATION AND EFFECTIVE RENAL PLASMA FLOW,

Corporate Author : ARMY MEDICAL RESEARCH LAB FORT KNOX KY

Personal Author(s) : Talso, P. J. ; Crosley, A. P., Jr. ; Clarke, R. W.

Report Date : 27 OCT 1947

Pagination or Media Count : 7

Abstract : Studies were made of the effects of the cold pressor test on renal function. Seven male volunteers who had no history of renal disease served as subjects. Glomerular filtration (as measured by mannitol clearance) and effective renal plasma flow (as measured by sodium para-aminohippurate clearance) were determined before, during and after immersion of the foot in ice water at 1 C for 15 minutes. In 6 out of 7 subjects both glomerular filtration rate and effective renal plasma flow decreased either during the application of the cold stimulus or within approximately 30 minutes thereafter. In no subject did the effect persist longer. The average decrease in glomerular filtration rate and effective renal plasma flow, as compared with the control values, were 14% and 21%, respectively. (Author)

Descriptors :   (*KIDNEYS, COLD WEATHER TESTS), PHYSIOLOGY, BLOOD CIRCULATION, METABOLISM, BLOOD PLASMA, FEET, COOLING, STRESS(PHYSIOLOGY).

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE