Accession Number : AD0821971

Title :   TRANSPORT OF MACROMOLECULES ACROSS BIOLOGICAL MEMBRANES.

Descriptive Note : Final rept. 1 Jul 64-31 Aug 67,

Corporate Author : PHILCO-FORD CORP NEWPORT BEACH CA AERONUTRONIC DIV

Personal Author(s) : Bean, R. C.

Report Date : 31 AUG 1947

Pagination or Media Count : 110

Abstract : In general, it may be safe to assume that, for small molecules, the study of transport relations may become a study of the energy of transition between aqueous and lipid phase, but the multitude of forces may make an extremely complex analysis necessary. For the case of the macromolecule, even more complexity will be involved, since the disturbance of the membrane lattice may be much larger than that in the movement of small molecules. In the analysis of the mechanisms, forces and energies, the lipid bilayer membrane, and its modifications, should provide an important tool, to be used in conjunction with other tools, to accumulate specific information. In this role it may provide much information which could not be obtained by other means but it must be used judiciously, in full recognition of its problems as well as advantages. (Author)

Descriptors :   (*MEMBRANES(BIOLOGY), TRANSPORT PROPERTIES), MEMBRANES, MOLECULES, PH FACTOR, PERMEABILITY, LIPIDS, IONS, PEPTIDES, DYES, PROTEINS, PHYSICAL PROPERTIES, RETICULOENDOTHELIAL SYSTEM, THEORY.

Subject Categories : Anatomy and Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE