Accession Number : AD0834403

Title :   SYNTHESIS OF 1.8-DIDESMETHYL-ACTINOMYCIN C1,

Corporate Author : ARMY BIOLOGICAL LABS FREDERICK MD

Personal Author(s) : Brockmann, Hans ; Seela, Frank

Report Date : 12 OCT 1966

Pagination or Media Count : 4

Abstract : The first synthetic actinomycin, which differs from all known natural and synthetic actinomycins in its chromophore, was obtained in crystallized form via the intermediate products I-V. Instead of 3-amino-1.8-dimethylphenoxazone-(2)-dicarbonic acid-(4.5) (actinocin (1)) it contains 3-amino-phenoxazone-(2)-dicarbonic acid-(4.5) (cinnabarinic acid (2)). (Author)

Descriptors :   (*ANTIBIOTICS, SYNTHESIS(CHEMISTRY)), PHARMACOLOGY.

Subject Categories : Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE