Accession Number : AD0839382

Title :   CHEMICAL BINDING OF PROTECTIVE AGENTS TO THE HUMAN STRATUM CORNEUM.

Descriptive Note : Final rept. Jul 65-Jul 68,

Corporate Author : HARVARD MEDICAL SCHOOL BOSTON MA DEPT OF DERMATOLOGY

Personal Author(s) : Fitzpatrick, Thomas B. ; Pathak, Madhukar A.

Report Date : JUL 1968

Pagination or Media Count : 224

Abstract : Report covers laboratory study and clinical trials on a series of chemical formulations to find means of chemically binding agents to skin elements or of permanent absorption to provide long term (7 days) protection from sunburn regardless of heavy sweating or washing actions. Results are reported in detail and tabulated. Two preparations were developed which were effective for long term exposure (4 hr) after single application and were resistant to washing action. Preparations did not interfere with tanning action and were cosmetically acceptable. Two were very effective under conditions of bright sun in dry climate or high elevation and snow environments. Stable binding to skin providing 7-day or longer protection was not achieved. (Author)

Descriptors :   (*BURNS(INJURIES), PROTECTION), (*SOLAR RADIATION, BURNS(INJURIES)), HUMANS, EXPOSURE(PHYSIOLOGY), SUN, EXERCISE(PHYSIOLOGY), PERSPIRATION, SKIN(ANATOMY), VITAMIN B COMPLEX, ETHANOLS, ESTERS, PERIODIC VARIATIONS, PHOTOSENSITIVITY(BIOLOGICAL), ULTRAVIOLET RADIATION.

Subject Categories : Biochemistry
      Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE