Accession Number : AD0841340

Title :   THE CULTURE OF CELLS FROM A 'CLOISONNE' GOAT KIDNEY.

Descriptive Note : Technical rept. Aug 65-Nov 67,

Corporate Author : EDGEWOOD ARSENAL ABERDEEN PROVING GROUND MD

Personal Author(s) : Wood, William O.

Report Date : JUL 1968

Pagination or Media Count : 27

Abstract : A study was made of comparative in vitro growth patterns of the 'cloisonne' and normal goat kidneys (Capra hircus) over long term cell cultivation. Strikingly different in gross appearance and microscopic analysis, each continues this distinctly dissimilar pattern in tissue culture. Pigmented thickening of renal basement membranes of the proximal convoluted tubules in the cortex of the 'cloisonne' kidney reveals evidence of possible continued production in vitro. Although possessing a well-defined pathological phenomenon in vitro, substantiated by electron microscopy, the 'cloisonne' kidney cell retains normal chromosome counts throughout serial subculture. Its counterpart, the normal control culture, continues its active proliferation without any of the abnormal morphological features found in the 'cloisonne' culture. (Author)

Descriptors :   *KIDNEYS), (*TISSUE CULTURE CELLS, GOATS, IN VITRO ANALYSIS, HISTOLOGY, PATHOLOGY, TISSUE CULTURE, MORPHOLOGY(BIOLOGY), ELECTRON MICROSCOPY, CHROMOSOMES, MEMBRANES(BIOLOGY), ORGANIC PIGMENTS.

Subject Categories : Anatomy and Physiology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE