Accession Number : AD0846603

Title :   Primary Irritation Evaluation Program, P.I.E.P. Report. Project Numbers 33-003-69 Thru 33-006-69.

Descriptive Note : Final rept.,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Rowe, Stephen E. ; Steinberg, Marshall

Report Date : 19 DEC 1968

Pagination or Media Count : 7

Abstract : Four candidate topically applied insect repellents, ENT-28926-Ga, ENT-28927-Ga, ENT-28930-Ga, and ENT-28951-Ga were evaluated for their potential to cause skin and eye irritation in New Zealand White Rabbits. None of the four compounds produced primary irritation of the intact skin or the skin surrounding an abrasion. ENT-28926-Ga produced moderate injury to the cornea and some injury to the conjunctiva. ENT-28927-Ga produced mild injury to the cornea and some injury to the conjunctiva. ENT's 28930-Ga and 28951-Ga produced severe injury to the cornea and the conjunctiva. It was recommended that the candidate repellents be resubmitted in the concentration and form in which they might be used, in order that the eye irritation potential can be reexamined. (Author)

Descriptors :   *INSECT REPELLENTS, TOXICITY, SKIN(ANATOMY), EYE, WOUNDS AND INJURIES, RABBITS, PATHOLOGY.

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE