Accession Number : AD0848995

Title :   Cultivation of Leptospira Strains on Different Nutritive Media,

Corporate Author : ARMY FOREIGN SCIENCE AND TECHNOLOGY CENTER WASHINGTON D C

Personal Author(s) : Todorova,R.

Report Date : 06 MAR 1969

Pagination or Media Count : 7

Abstract : Growth of four strains of Leptospira were studied on three nutritive media; Sademov, Kostrikina modified medium, and Korthof medium. Three series of vaccines were prepared and tested for sterility, innocuousness, and activity. Results indicated superior growth of Leptospira for a longer time on modified nutritive medium than on Korthof. A Pomona-type vaccine prepared from cultures on this medium effectively immunized animals. The modified medium has the advantages of easier and cheaper preparation than the other two, and is recommended for the future preparation of vaccine against Leptospira. (Author)

Descriptors :   (*LEPTOSPIRA, CULTURE MEDIA), NUTRITION, VACCINES, GROWTH(PHYSIOLOGY), IMMUNITY, BLOOD SERUM, LIVER, TISSUE EXTRACTS, USSR

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE