Accession Number : AD0874415

Title :   Marker Frequency Analysis Mapping of the Staphylococcus Aureus Chromosome,

Corporate Author : FORT DETRICK FREDERICK MD

Personal Author(s) : Altenbern, Robert A.

Report Date : AUG 1970

Pagination or Media Count : 19

Abstract : Marker frequency analysis of several strains of Staphylococcus aureus has yielded a genomic map supporting the map derived by synchronous chromosomal replication. Gene orders of exponential cells obtained by using reference cells with completed chromosomes effected by chloramphenicol or by phenethyl alcohol treatment were identical, suggesting that these two agents halted chromosomal replication at a common terminus. In several strains, the pantothenate or acriflavine resistance locus changed its relative chromosomal position during exponential growth. The data indicate that more than one chromosomal growing point occurred during logarithmic growth in nonsynthetic medium. (Author)

Descriptors :   *CHROMOSOMES), (*STAPHYLOCOCCUS AUREUS, GENETICS, MARKERS, CHLORAMPHENICOL, GROWTH(PHYSIOLOGY), EXPONENTIAL FUNCTIONS, ETHANOLS, FREQUENCY.

Subject Categories : Anatomy and Physiology
      Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE