Accession Number : ADA016920

Title :   Hazard Evaluation of Candidate Face Net Impregnant ENT-20127, Pentyl Mandelate.

Descriptive Note : Final rept. May 73-Mar 75,

Corporate Author : ARMY ENVIRONMENTAL HYGIENE AGENCY ABERDEEN PROVING GROUND MD

Personal Author(s) : Weeks,Maurice H. ; Pope,Conrad R. ; Macko,Joseph A. , Jr

Report Date : 23 OCT 1975

Pagination or Media Count : 19

Abstract : A hazard evaluation of the candidate face net impregnant technical grade pentyl mandelate (ENT 201127) was performed by means of laboratory animal studies using rats, rabbits, and guinea pigs. The technical grade compound did not produce primary irritation when applied to the intact or abraded skin of rabbits. No corneal injury, iritis or conjunctivitis was observed after a single application of the technical grade compound to the eyes of rabbits. Data indicate little acute toxic hazard from accidental ingestion. ENT-20127 did not produce skin sensitivization in guinea pigs. Acute aerosol as well as acute and subchronic saturated vapor inhalation exposures of rats resulted experimentally in no deleterious effect.

Descriptors :   *Insect repellents, *Toxicology, *Irritant compounds, Lethal dosage, Bioassay, Laboratory animals, Skin(Anatomy), Eye, Exposure(Physiology), Inhalation, Ingestion(Physiology)

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE