Accession Number : ADA018967

Title :   Genetics of Novel Hybrid Bacteriophage and Development of Generalized Transducing System for 'Salmonella typhosa'.

Descriptive Note : Annual progress rept. no. 1, 1 Jan-31 Dec 75,

Corporate Author : TEMPLE UNIV PHILADELPHIA PA SCHOOL OF MEDICINE

Personal Author(s) : Yamamoto,Nobuto

Report Date : 29 DEC 1975

Pagination or Media Count : 10

Abstract : Various hybrid phages between coliphage and Salmonella phage were isolated using bacterial hybrids between E. coli and Salmonella typhimurium. These hybrid phage species were genetically mapped for homology with their parental phages. The role of various parental phage genes of hybrid phages for their replication in S. typhimurium, E. coli-S. typhosa hybrid and E. coli was carefully analyzed. Essential bacterial and viral functions for replication of the hybrid phages in these bacterial strains provided important information for the process of viral infection. The P22-lamda hybrids have capabilities for antigen conversion and generalized transduction in both S. typhimurium and E. coli-S. typhimurium hybrid.

Descriptors :   *Bacteriophages, *Genetics, *Escherichia coli, *Salmonella typhosa, *Coliphage, Bacteria, Hybrid systems, Genes

Subject Categories : Microbiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE