Accession Number : ADA019089

Title :   The Reaction Pattern of Liver-Peroxysomes (=Microbodies) during Cell Injury,

Corporate Author : ARMY MEDICAL RESEARCH INST OF INFECTIOUS DISEASES FREDERICK MD

Personal Author(s) : Riede,U. N. ; Rohr,H. P.

Report Date : 06 JAN 1976

Pagination or Media Count : 17

Abstract : The quantitative relation of dependency of microbodies, mitochondria, and cristae membrances confirms the participation of the microbodies in cellular metabolism. There is still lacking today the demonstration of 'peroxysomal diseases' but a number of idiopathic diseases must be considered from this viewpoint. These include hypercholesterinemia, hyperlipidemia, and hyperuremia (Hruban et al, 1972). It is possible that an insufficiency of the microbodies in the form of a defective microbody genesis or defective enzyme presence might lead to an intracellular accumulation of toxic metabolites which may have repercussions on other metabolic compartments.

Descriptors :   *Cells(Biology), Enzymes, Liver, Cytology, Wounds and injuries, Mitochondria, Metabolism, Pathology, Translations, West Germany

Subject Categories : Medicine and Medical Research

Distribution Statement : APPROVED FOR PUBLIC RELEASE