Accession Number : ADA019177

Title :   A Squirrel Monkey Behavioral Model for Human Acute Mountain Sickness,

Corporate Author : ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MASS

Personal Author(s) : Banderet,L. E.

Report Date : APR 1975

Pagination or Media Count : 24

Abstract : The research determined if squirrel monkey (SM) behavioral changes at altitude are a model for human acute mountain sickness (AMS). Two monkeys were studied at 0, 3700, 4000, and 4300 m in chambers instrumented for continuous measurement of climbing and chamber location. Food and water consumption and body weight were measured daily. All measures were incrementally sensitive to altitude levels and their time courses resembled that for human AMS. In another study, behavioral changes at altitude were minimal when a treatment regime beneficial for man was investigated. Thus, SM behaviors at altitude appear a promising model for the evaluation of prophylactic strategies and study of human AMS.

Descriptors :   *Stress(Physiology), *High altitude, *Hypoxia, Monkeys, Laboratory animals, Experimental data, Behavior, Humans, Comparison, Prophylaxis

Subject Categories : Stress Physiology

Distribution Statement : APPROVED FOR PUBLIC RELEASE