Accession Number : ADA019592

Title :   The Amelioration of Acute Mountain Sickness by Staging and Acetazolamide,

Corporate Author : ARMY RESEARCH INST OF ENVIRONMENTAL MEDICINE NATICK MASS

Personal Author(s) : Evans,W. O. ; Robinson,S. M. ; Horstman,D. H. ; Jackson,R. E. ; Weiskopf,R. B.

Report Date : MAY 1975

Pagination or Media Count : 27

Abstract : Treatment by four days residence at 1600m plus the administration of 500 mg acetazolamide twice a day for the last two days at 1600m and the first two days at 4300m was compared with no treatment prior to ascent to 4300m for prophylaxis of acute mountain sickness. The treatment successfully prevented almost all symptoms of acute mountain sickness. It had no effect on the diminished capacity for maximal or prolonged heavy physical work. The treatment produced a relative acidosis and a comparatively greater arterial oxygen tension at 4300m.

Descriptors :   *High altitude, *Acetazolamide, *Stress(Physiology), Acclimatization, Therapy, Prophylaxis, Acidosis, Chemotherapy, Chemotherapeutic agents, Dosage, Dose rate

Subject Categories : Stress Physiology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE