Accession Number : ADA112971

Title :   The Mutagenic Potential of 2,4-diamino-6-(2'-napthyl-sulfonyl) quinazoline.

Descriptive Note : Final rept. Oct-Nov 81,

Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s) : Sauers,Leonard J ; Fruin,John T

PDF Url : ADA112971

Report Date : Feb 1982

Pagination or Media Count : 43

Abstract : The mutagenic potential of 2,4-diamino-6-(2'napthyl-sulfonyl) quinazoline (WR158122) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .001 mg/plate to 3.2 x 10 to the minus 7th power mg/plate. It was determined that the test substance did not have mutagenic potential.

Descriptors :   *Toxicity, *Mutagens, *Quinazolines, Bioassay, Salmonella, Microsomes, Dosage, Response(Biology), Molecular structure, Strains(Biology), Tables(Data)

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE