Accession Number : ADA112971
Title : The Mutagenic Potential of 2,4-diamino-6-(2'-napthyl-sulfonyl) quinazoline.
Descriptive Note : Final rept. Oct-Nov 81,
Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA
Personal Author(s) : Sauers,Leonard J ; Fruin,John T
PDF Url : ADA112971
Report Date : Feb 1982
Pagination or Media Count : 43
Abstract : The mutagenic potential of 2,4-diamino-6-(2'napthyl-sulfonyl) quinazoline (WR158122) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from .001 mg/plate to 3.2 x 10 to the minus 7th power mg/plate. It was determined that the test substance did not have mutagenic potential.
Descriptors : *Toxicity, *Mutagens, *Quinazolines, Bioassay, Salmonella, Microsomes, Dosage, Response(Biology), Molecular structure, Strains(Biology), Tables(Data)
Subject Categories : Toxicology
Distribution Statement : APPROVED FOR PUBLIC RELEASE