Accession Number : ADA112982

Title :   The Mutagenic Potential of: Chloroquine Phosphate USP.

Descriptive Note : Final rept. Oct-Nov 81,

Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s) : Sauers,Leonard J ; Fruin,John T

PDF Url : ADA112982

Report Date : Mar 1982

Pagination or Media Count : 41

Abstract : The mutagenic potential of chloroquine phosphate USP (WR1522) was assessed by using the Ames Salmonella/Mammalian Microsome Mutagenicity Assay. Tester strains TA 98, TA 100, TA 1535, TA 1537 and TA 1538 were exposed to doses ranging from 1 mg/plate to .00032 mg/plate. It was determined that the tested substance did not have mutagenic potential. (Author)

Descriptors :   *Toxicity, *Mutagens, *Chloroquine, Phosphates, Bioassay, Microsomes, Salmonella, Antimalarials, Dosage, Response(Biology), Molecular structure

Subject Categories : Toxicology
      Pharmacology

Distribution Statement : APPROVED FOR PUBLIC RELEASE