Accession Number : ADA113586

Title :   Dermal Sensitization Potential of Candidate Insect Repellents: LAIR Formulation (CHF1) N-(n-octyl) glutarimide (CHR2) N-(n-hexyl) glutarimide (CHR3) (E) 1,2,3,4-tetrahydro-6-methyl-1-(2-methyl-1-oxo-2-butenyl)quinoline (CHR5) 1,2,3,4-tetrahydro-6-methyl-1-(3-methyl-1-oxo-2-butenyl) quinoline (CHR6).

Descriptive Note : Final rept. 22 Apr-8 Jun 81,

Corporate Author : LETTERMAN ARMY INST OF RESEARCH PRESIDIO OF SAN FRANCISCO CA

Personal Author(s) : Fruin,John T ; Hanes,Martha A ; Black,Kenneth ; Gildengorin,Virginia L

PDF Url : ADA113586

Report Date : Feb 1982

Pagination or Media Count : 41

Abstract : Arthropods represent a potential disease threat to U.S. Military Forces; consequently, a program to develop improved insect repellents was developed. The dermal sensitization potential of candidate insect repellents was determined using guinea pigs. Test substances CHF1, CHR2, and CHR3 were clearly non-sensitizing. CHR5 and CHR6 were irritating, possibly sensitizing, and should be retested. (Author)

Descriptors :   *Insect repellents, *Toxicity, *Quinolines, Sensitivity, Skin(Anatomy), Skin tests, Guinea pigs, Molecular structure

Subject Categories : Toxicology

Distribution Statement : APPROVED FOR PUBLIC RELEASE