Accession Number : ADA113786

Title :   Robust Comparison of Three-Dimensional Shapes with an Application to Protein Molecule Configurations.

Descriptive Note : Technical rept.,


Personal Author(s) : Siegel,Andrew F ; Pinkerton,John R

PDF Url : ADA113786

Report Date : Mar 1982

Pagination or Media Count : 21

Abstract : Robust statistical methods have recently been shown to have desirable properties when used for the identification of similarities and differences in shape. We present a generalization of the two-dimensional repeated median algorithm to three and higher dimensions. The extension is achieved using a duality between orthogonal and skew-symmetric matrices, which permits the definition of a median of a collection of orthogonal matrices. The methods are illustrated by comparing the predicted three-dimensional configuration of a protein molecule to a refined structure that had been found using nuclear magnetic resonance techniques. (Author)

Descriptors :   *Proteins, *Molecules, *Molecular structure, *Statistical processes, Geometric forms, Shape, Three dimensional, Algorithms, Two dimensional, Comparison, Patterns, Matching, Resistance, Symmetry, Matrices(Mathematics), Nuclear magnetic resonance, Fitting functions(Mathematics)

Subject Categories : Biochemistry
      Statistics and Probability

Distribution Statement : APPROVED FOR PUBLIC RELEASE